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  • Pharmacology in Drug Discovery and Development : Understanding Drug Response
    Pharmacology in Drug Discovery and Development : Understanding Drug Response

    Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action.Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems.New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters.The newly developed companion website hosts further educational resources to complement the book.As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

    Price: 76.95 £ | Shipping*: 0.00 £
  • Hypnotic Response
    Hypnotic Response


    Price: 13.49 £ | Shipping*: 3.99 £
  • Panic Response
    Panic Response

    *SHORTLISTED FOR THE 2021 FORWARD PRIZE FOR BEST SINGLE POEM*From the mercurial mind of award-winning poet John McCullough comes his darkest and most experimental book to date.Panic Response puts personal and cultural anxiety under the microscope.It is full of things that shimmer, quiver and fizz: plankton glowing at low tide; brain tissue turning to glass; a basketball emerging from the waves, covered in barnacles.These are poems of uncertainty but also of hope, which move beyond the breathlessness of panic towards luminescence and solidarity.

    Price: 9.99 £ | Shipping*: 3.99 £
  • Lethal Response
    Lethal Response

    Lethal Response follows the aftermath of an epic and bloody battle.Law enforcement headed by Major Paul Stafford, destroyed a huge drug smuggling and people trafficking ring, in an operation code named, TRASHED. Stafford's previous success in smashing international terrorist groups and criminal gangs have seen him and his crew seconded to Hampshire Constabulary. The police are jubilant; they feel they have gained the upper hand. But without evidence to charge anyone with the horrific murder of his long term sergeant and friend, and the cold blooded shooting of an innocent colleague, Stafford feels he's failed. He determines to do whatever it takes to hunt the killers down. Crime bosses are fighting back. Witnesses are being killed to stop them from testifying - Stafford's colleagues and friends continue to be targeted. Stafford is desperate to protect the people he cares about. And bring the crime lords and their hitmen to justice. Paul Stafford's kind of justice. LETHAL RESPONSE, a breathtaking story following on from the author's stunning debut novel, TRASHED.

    Price: 10.00 £ | Shipping*: 3.99 £
  • How can one forget culture and heritage?

    One can forget culture and heritage by not actively engaging with it, by being disconnected from one's roots and community, and by prioritizing other aspects of life over preserving and celebrating one's cultural identity. This can happen through assimilation into a different culture, lack of exposure to one's own cultural traditions and practices, and a lack of interest in learning about one's heritage. Additionally, societal pressures and discrimination can also contribute to the erasure of one's culture and heritage.

  • What does it mean that no response is also a response?

    When no response is given, it can still convey a message or signal a lack of interest or agreement. It may indicate disapproval, indifference, or a desire to avoid confrontation. In some cases, choosing not to respond can be a deliberate strategy to communicate a message indirectly. Therefore, it is important to consider the context and relationship dynamics when interpreting the meaning of no response.

  • What is the transfer function for the ramp response and the impulse response?

    The transfer function for the ramp response is given by H(s) = 1/s^2, where s is the Laplace variable. This transfer function represents a second-order system with a pole at the origin. On the other hand, the transfer function for the impulse response is H(s) = 1, which represents a first-order system with no poles. The ramp response is used to analyze the steady-state behavior of a system, while the impulse response is used to analyze the transient behavior.

  • Why are response time and response rate no longer visible on eBay Kleinanzeigen?

    Response time and response rate are no longer visible on eBay Kleinanzeigen because the platform has shifted its focus towards promoting a more user-friendly experience for both buyers and sellers. By removing these metrics, eBay Kleinanzeigen aims to reduce the pressure on users to respond quickly and instead encourages more meaningful interactions. This change also aligns with the platform's goal of fostering a sense of community and trust among its users, rather than solely focusing on transactional aspects.

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  • First Response
    First Response

    From the bestselling author of the Spider Shepherd and Jack Nightingale series comes First Response, the utterly addictive new thriller by Stephen Leather.London is under siege. Nine men in suicide vests primed to explode hold hostages in nine different locations around the city, and are ready to die for their cause. Their mission: to force the government to release jihadist prisoners from Belmarsh Prison. Their deadline: 6 p.m. Today. But the bombers are cleanskins, terrorists with no obvious link to any group, and who do not appear on any anti-terror watch list.What has brought them together on this one day to act in this way?Mo Kamran is the Superintendent in charge of the Special Crime and Operations branch of the Met.As the disaster unfolds and the SAS, armed police, and other emergency services rush to the scenes, he is tasked with preventing the biggest terrorist outrage the capital has ever known. But nothing is what it seems. And only Kamran has the big picture. Will anyone believe him?A chillingly plausible and pulse-pounding depiction of how London might be held to ransom in a concerted terrorist attack: this is thriller writing at its very best.

    Price: 9.99 £ | Shipping*: 3.99 £
  • The Contemplative Response : Leadership and ministry in a distracted culture
    The Contemplative Response : Leadership and ministry in a distracted culture

    Following on from the success of The Contemplative Minister, Ian Cowley offers new insight and greater depth for church leaders in a distracted world.Ian emphasises that the true self finds peace in resting in the love of God.He addresses the compulsions of our consumerist culture and calls those in leadership to an inner life of truthfulness, self-knowledge and self-discipline.Praise for Ian's previous book: 'An immensely readable tour de force' Church Times

    Price: 8.99 £ | Shipping*: 3.99 £
  • Call and Response
    Call and Response

    'A terrific collection' Monica Ali, author of Brick Lane and Love MarriageA Most Anticipated Title for Oprah Daily, Essence, BuzzFeed, The Millions and Brittle PaperFull of heart and humour, Gothataone Moeng's first collection, set between the rural village of Serowe and the thrumming capital city of Gaborone, captures a chorus of voices from a country in flux. Meet a young woman who has worn the same mourning clothes for almost a year, and a teenage girl who shies away from the room where her once vibrant aunt lies dying.Elsewhere, watch as a younger sister hides her romantic exploits from her family while her older brother openly flaunts his infidelities, and a traveller returns home laden with confusion and shame. Moeng, part of a new generation of writers coming out of Africa whose work is exploding onto the literary scene, offers us an insight into communities, experiences and landscapes through these cinematic stories peopled with unforgettable female protagonists. 'A good short story is a bit of alchemy, showing us so much in so few pages.Gothataone Moeng's debut collection does this over and over.' Rumaan Alam, author of Leave the World Behind

    Price: 16.99 £ | Shipping*: 3.99 £
  • Call and Response
    Call and Response

    'A terrific collection' Monica Ali, author of Brick Lane and Love MarriageA Most Anticipated Title for Oprah Daily, Essence, BuzzFeed, The Millions and Brittle PaperFull of heart and humour, Gothataone Moeng's first collection, set between the rural village of Serowe and the thrumming capital city of Gaborone, captures a chorus of voices from a country in flux. Meet a young woman who has worn the same mourning clothes for almost a year, and a teenage girl who shies away from the room where her once vibrant aunt lies dying.Elsewhere, watch as a younger sister hides her romantic exploits from her family while her older brother openly flaunts his infidelities, and a traveller returns home laden with confusion and shame. Moeng, part of a new generation of writers coming out of Africa whose work is exploding onto the literary scene, offers us an insight into communities, experiences and landscapes through these cinematic stories peopled with unforgettable female protagonists. 'A good short story is a bit of alchemy, showing us so much in so few pages.Gothataone Moeng's debut collection does this over and over.' Rumaan Alam, author of Leave the World Behind

    Price: 9.99 £ | Shipping*: 3.99 £
  • What is the difference between non-specific immune response and specific immune response?

    The non-specific immune response, also known as innate immunity, is the body's first line of defense against pathogens. It includes physical barriers like the skin, as well as cellular and chemical defenses such as inflammation and phagocytosis. This response is not targeted to a specific pathogen and does not provide long-term immunity. On the other hand, the specific immune response, also known as adaptive immunity, is a targeted response to a specific pathogen. It involves the activation of T and B lymphocytes, which produce antibodies and memory cells that provide long-term immunity against a particular pathogen. This response is highly specific and has memory, allowing the body to mount a faster and more effective response upon subsequent exposure to the same pathogen.

  • Is man a creature of nature or culture, or is culture the nature of man?

    Man is a complex being influenced by both nature and culture. While humans are inherently part of the natural world, our behaviors, beliefs, and practices are largely shaped by the societies we live in. Culture can be seen as the nature of man in the sense that it is a fundamental aspect of human existence, shaping our identities and interactions with the world. Ultimately, the relationship between nature and culture is intertwined in shaping the essence of humanity.

  • Is man a being of nature or culture, or is culture the nature of man?

    Man is a being of both nature and culture. While humans are inherently a part of the natural world, our ability to create and participate in culture sets us apart from other species. Culture shapes our beliefs, behaviors, and interactions with the world, becoming an essential part of our identity. Therefore, culture can be seen as the nature of man, as it influences and defines our existence in profound ways.

  • 'Hillfee urgently needs a response.'

    Hillfee urgently needs a response to address the situation at hand and make informed decisions. Without a prompt response, the issue may escalate or lead to further complications. It is crucial to prioritize Hillfee's request and provide a timely and effective solution to ensure a positive outcome. Swift action is necessary to prevent any negative impact on Hillfee's well-being or the situation at hand.

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