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Evolution, Composition and Regulation of Supernumerary B Chromosomes
Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.
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Abnormal Chromosomes : The Past, Present, and Future of Cancer Cytogenetics
Explore the past, present, and future of cancer cytogeneticsIn Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs.Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients.The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics. The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders.From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process?How was information of this nature put to good use in the clinical management of cancer patients?Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers: A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developedComprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancerA detailed chronological resume of cancer cytogenetic discoveries during the 20th centuryIn-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populationsA discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics was written for everyone with a scientific or clinical interest in cancer, especially how acquired chromosome abnormalities lead to neoplastic transformation.The book teaches how cytogenetic analyses contribute to a better understanding of tumorigenesis, but also how the finding of specific chromosome aberrations can be crucial for the diagnosis, prognosis, and management of cancer patients.
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The Wolf : Culture, Nature, Heritage
New insights into the changing human attitudes towards wild nature through the depiction of wolves in human culture and heritage. Few animals arouse such strong opinion as the wolf.It occupies a contested, ambiguous, yet central role in human culture and heritage.It appears as both an inspirational emblem of the wild and an embodiment of evil.Offering a mirror to different human attitudes, beliefs, and values, the wolf is, arguably, the species that plays the greatest role in shaping our views on what nature is or should be. North America and, more recently, Europe have witnessed a remarkable return of the grey wolf (Canis lupus, and its close relative the Eurasian wolf, Canis lupus lupus) to eco-systems.The essays collected here explore aspects of this recovery, and consider the history, literature and myth surrounding this iconic species.There are chapters on wolf taxonomy, including the coywolf, the red wolf, and the many faces of the dingo.We also meet the Tasmanian wolf and encounter Nazi Werewolves from Outer Space.The book explores the challenges of separating fact from fiction and superstition, and our willingness to co-exist with large carnivores in the twenty-first century.Biologists, historians, anthropologists, cultural theorists, conservationists and museologists will all find riches in the detail presented in this wolf collection.
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Exploration and Discovery
The discovery and mapping of the world, its peoples, oceans and continents, are the result of centuries of exploration.This book traces the history of such travel and the pioneers who pushed back the frontiers of the known world.It explains the reasons for their journeys, whether out of scientific curiosity, to create trading opportunities, to spread religious beliefs or for personal gain or glory.With the aid of over 250 illustrations, maps and photographs, this accessible reference work captures all the excitement and spirit of adventure.
Price: 7.99 £ | Shipping*: 3.99 £
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The Nature Adventure Book : 40 activities to do outdoors
Get curious, get creative, get outside! Get close to nature with this outdoor project book. This is the perfect gift for adventurous children, as they play their way through 40 crafts and games to be done outside. Inside the pages of this activity book for kids, you'll discover:- More than 40 inspiring outdoor activities split into four sections: adventure skills, nature detective, wild art, and sensory games- Outdoor crafts that are explained clearly through beautiful photography and step-by-step instructions - Colourful and fun pages with illustrations mixed in throughout about fun things to do in natureNature is a destination, but you don't have to travel anywhere to find it!Perfect for kids aged 5-7 years, this nature book includes heaps of ideas for outdoor fun that can be done on-the-go, in your neighbourhood, or at your local park.It's the ultimate way to keep even the tiniest of explorers entertained for hours. From leading a friend on a journey to meet a tree and building a twig raft to collecting leaves on a nature walk and creating nature-inspired art, children will love discovering the magic of nature.It's the perfect gift for adventurous kids who love being outdoors and for parents looking for creative outdoor projects and an escape from digital entertainment.
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See Inside Exploration and Discovery
Journey into the unknown with real-life explorers from times gone by, in this fascinating lift-the-flap history book.Features some of the most famous and daring explorers and missions from history, including Marco Polo's journey from Italy to China in 1271, Christopher Columbus' discovery of the 'New World', the new frontiers of space exploration and lots more.With over 70 flaps to lift to reveal facts such as who the first explorers were, how the Ancient Greeks drew early maps of the world and the places that brave men and women are still exploring today.A compelling book for young explorers, full of fascinating history, geography and adventure.
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Kids Adventure Toys Kit 14PCS Outdoor Nature Exploration Toys Elescope Dragonfly Butterfly Catching
Kids Adventure Toys Kit 14PCS Outdoor Nature Exploration Toys Elescope Dragonfly Butterfly Catching
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Genetics 101 : From Chromosomes and the Double Helix to Cloning and DNA Tests, Everything You Need to Know about Genes
A clear and straightforward explanation of genetics in this new edition of the popular 101 series.Our genetic makeup determines so much about who we are, and what we pass on to our children—from eye color, to height, to health, and even our longevity.Genetics 101 breaks down the science of how genes are inherited and passed from parents to offspring, what DNA is and how it works, how your DNA affects your health, and how you can use your personal genomics to find out more about who you are and where you come from. Whether you’re looking for a better scientific understanding of genetics, or looking into your own DNA, Genetics 101 is your go-to source to discover more about both yourself and your ancestry.
Price: 12.99 £ | Shipping*: 3.99 £
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