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Open Access Databases and Datasets for Drug Discovery
Open Access Databases and Datasets for Drug Discovery Timely resource discussing the future of data-driven drug discovery and the growing number of open-source databases With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers.The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated.The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data.The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases.The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.Contributed to and edited by experts with long-time experience in the field, Open Access Databases and Datasets for Drug Discovery includes information on: An extensive listing of open access databases and datasets for computer-aided drug designPubChem as a chemical database for drug discovery, DrugBank Online, and bioisosteric replacement for drug discovery supported by the SwissBioisostere databaseThe Protein Data Bank (PDB) and macromolecular structure data supporting computer-aided drug design, and the SWISS-MODEL repository of 3D protein structures and models PDB-REDO in computational aided drug design (CADD), and using Pharos/TCRD for discovering druggable targets Unmatched in scope and thoroughly reviewing small and large open data sources relevant for rational drug design, Open Access Databases and Datasets for Drug Discovery is an essential reference for medicinal and pharmaceutical chemists, and any scientists involved in the drug discovery and drug development.
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Japan's World Heritage Sites : Unique Culture, Unique Nature
Japan's World Heritage Sites presents the exquisite temples, shrines, gardens, castles and natural wonders found throughout Japan which have now been declared UNESCO World Heritage Sites.This new edition has more convenient size and includes many newly-designated UNESCO sites including:Christian Sites in Nagasaki that tell the extraordinary story of Japan's Christians who continued to practice their faith in secret under penalty of death during Japan's feudal eraMeiji Industrial Sites which tell of the nation's rapid modernization during the Meiji periodThe Munakata Shrine to seafaring deities on a forbidding islandThe Tomioka Silk Mill which became a leader in Japan's export driveThe National Museum of Western Art, an architectural gem designed by Le CorbusierJapan expert John Dougill personally traveled to each of these sites to research this book.He tells how his journey led him from the sub-Arctic island of Hokkaido to the sub-tropical islands of the Okinawan archipelago and beyond.Tag along as he describes each place in loving detail and talks about its special historical and cultural features, including: Mount Fuji, Japan's tallest and most sacred volcano.Located on Honshu Island near Tokyo, Mt. Fuji is considered the sacred center of Japan. Himeji Castle, a monument from Japan's long feudal history.Also known as Egret Castle, because it looks like a bird taking off in flight. Horu-ji Temple, the world's oldest surviving wooden structure—a center of Buddhist learning that still serves as a seminary and monasteryThe Hiroshima Peace Memorial or Atomic-Bomb Dome—one of the few structures to partially survive the atomic blast in 1945The Ogasawara Islands, a remote archipelago of over 30 islands including Iwo Jima, that is home to rare wildlife and spectacular scenery. Readers will learn how Japan became involved with the World Heritage Sites program back in 1993, the importance of these designations, and their popularity in Japan and abroad today.Whether you are planning to travel to Japan or just enjoy learning more about this history of this unique land, Japan's World Heritage Sites is sure to inspire.
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Exploration and Discovery
The discovery and mapping of the world, its peoples, oceans and continents, are the result of centuries of exploration.This book traces the history of such travel and the pioneers who pushed back the frontiers of the known world.It explains the reasons for their journeys, whether out of scientific curiosity, to create trading opportunities, to spread religious beliefs or for personal gain or glory.With the aid of over 250 illustrations, maps and photographs, this accessible reference work captures all the excitement and spirit of adventure.
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Access
'Access', the second album by Major Murphy, is an album born out of being at a crossroads. It's also, without question, an album to blast at an unruly volume to soundtrack an experience one might have standing at that crossroads. It's remarkably cohesive - a striking relic in an age where ardent and true 'album-making' is a fading art form full of heavy rock'n'roll sounds and textured atmospheres fused with pro-idea, hyper-creative jittery warmth. In nine songs, it somehow takes a listener backwards and forwards at once, reckoning with intrinsic anxieties while conceptualizing a fantastical and vibrant happening, soothing in its familia familiar, occasionally childlike tone.
Price: 13.99 £ | Shipping*: 3.99 £
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How can one forget culture and heritage?
One can forget culture and heritage by not actively engaging with it, by being disconnected from one's roots and community, and by prioritizing other aspects of life over preserving and celebrating one's cultural identity. This can happen through assimilation into a different culture, lack of exposure to one's own cultural traditions and practices, and a lack of interest in learning about one's heritage. Additionally, societal pressures and discrimination can also contribute to the erasure of one's culture and heritage.
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How can I access the travel agency database?
To access the travel agency database, you will typically need to have login credentials provided by the agency. Once you have the necessary login information, you can access the database through a secure online portal or software system. If you are unsure about how to access the database, you can reach out to the travel agency's IT support team for assistance.
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How do I access my access point?
To access your access point, you will need to connect to the same network that the access point is on. Once connected, open a web browser and enter the IP address of the access point in the address bar. You may need to enter a username and password to log in to the access point's settings. From there, you can configure and manage the access point as needed.
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Is man a creature of nature or culture, or is culture the nature of man?
Man is a complex being influenced by both nature and culture. While humans are inherently part of the natural world, our behaviors, beliefs, and practices are largely shaped by the societies we live in. Culture can be seen as the nature of man in the sense that it is a fundamental aspect of human existence, shaping our identities and interactions with the world. Ultimately, the relationship between nature and culture is intertwined in shaping the essence of humanity.
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Access
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The Nature Adventure Book : 40 activities to do outdoors
Get curious, get creative, get outside! Get close to nature with this outdoor project book. This is the perfect gift for adventurous children, as they play their way through 40 crafts and games to be done outside. Inside the pages of this activity book for kids, you'll discover:- More than 40 inspiring outdoor activities split into four sections: adventure skills, nature detective, wild art, and sensory games- Outdoor crafts that are explained clearly through beautiful photography and step-by-step instructions - Colourful and fun pages with illustrations mixed in throughout about fun things to do in natureNature is a destination, but you don't have to travel anywhere to find it!Perfect for kids aged 5-7 years, this nature book includes heaps of ideas for outdoor fun that can be done on-the-go, in your neighbourhood, or at your local park.It's the ultimate way to keep even the tiniest of explorers entertained for hours. From leading a friend on a journey to meet a tree and building a twig raft to collecting leaves on a nature walk and creating nature-inspired art, children will love discovering the magic of nature.It's the perfect gift for adventurous kids who love being outdoors and for parents looking for creative outdoor projects and an escape from digital entertainment.
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Adventure Time: Pirates of the Enchiridion Nintendo Switch Access Link
This product is a brand new and unused Adventure Time: Pirates of the Enchiridion Nintendo Switch Access Link
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10pcs 86X86mm Access control switch access control machine switch access control EXIT switch
10pcs 86X86mm Access control switch access control machine switch access control EXIT switch
Price: 11.69 € | Shipping*: 9.57 €
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Is man a being of nature or culture, or is culture the nature of man?
Man is a being of both nature and culture. While humans are inherently a part of the natural world, our ability to create and participate in culture sets us apart from other species. Culture shapes our beliefs, behaviors, and interactions with the world, becoming an essential part of our identity. Therefore, culture can be seen as the nature of man, as it influences and defines our existence in profound ways.
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Which hobbies involve being outdoors in nature?
Hobbies that involve being outdoors in nature include hiking, birdwatching, gardening, camping, fishing, and photography. These activities allow individuals to connect with the natural world, breathe in fresh air, and enjoy the beauty of the outdoors. Engaging in these hobbies can also provide physical and mental health benefits, such as reducing stress and increasing physical activity.
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Is culture a form of nature?
Culture is not a form of nature, but rather a product of human society. While culture can be influenced by nature and the environment, it is distinct in that it is created, shared, and passed down through generations by humans. Nature refers to the physical world and natural phenomena, while culture encompasses the beliefs, customs, arts, and social behaviors of a particular group of people.
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How can I access one Access Point from another Access Point when I am at an Internet access point?
To access one Access Point from another Access Point when you are at an Internet access point, you can use a Virtual Private Network (VPN) connection. By connecting to a VPN, you can securely access resources on one network from another network, such as accessing one Access Point from another. This allows you to establish a secure connection between the two Access Points and access the desired resources remotely. Additionally, you can use remote desktop software or SSH (Secure Shell) to access the other Access Point from your current location.
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